产品货号：
Z26746
中文名称：
SMURF1抗体
英文名称：
Anti-SMURF1 Antibody
产品规格：
0.1mg
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-SMURF1 Antibody |
| 指标别名 | SMAD specific E3 ubiquitin protein ligase 1;SMURF1 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | ELISA,WB,IHC |
| 基因名称 | SMURF1 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | SMURF1 antibody was raised against a 16 amino acid peptide near the amino terminus of human SMURF1.The immunogen is located within amino acids 180 - 230 of SMURF1. |
| 计算分子量 | 86kDa |
| 成分 | SMURF1 antibody is supplied in PBS containing 0.02% sodium azide. |
| 纯化方式 | SMURF1 antibody is affinity chromatography purified via peptide column. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 4℃可保存3个月，-20℃可保存1年。 |
| 背景资料 | SMURF1 (SMAD ubiquitin regulatory factor 1) is a negative regulator of TGF-beta signaling (1).SMURF1 and SMURF2 are members of HECT domain E3 ubiquitin ligase which are involved in the enzymatic reactions of the Ub conjugating pathway (1,2).SMURF1 negatively regulates osteoblast activity and response to bone morphogenesis protein (BMP) through controlling MEKK2 degradation (3).SMURF1 has recently been shown to play a role in breast cancer cell migration and invasion through the downregulation of RhoA (4). |
| Uniprot ID | Q9HCE7 |
| 基因名全称 | SMAD specific E3 ubiquitin protein ligase 1 |
| 蛋白名全称 | SMAD specific E3 ubiquitin protein ligase 1 |
| 推荐稀释比 | SMURF1 body can be used for detection of SMURF1 by Western blot at 1 ～ 2μg/mL.Antibody can also be used for Immunohistochemistry starting at 5μg/mL.Antibody validated:Western Blot in human samples and Immunohistochemistry in rat samples.All other applications and species not yet tested. |
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